Peter B. Dervan (born June 28, 1945) received his
early education in Boston, Massachusetts (B. S., Boston College,
1967). He began research in physical organic chemistry working with
Jerome A. Berson at Yale University. After earning his Ph.D degree in
1972, he spent a year at Stanford University as an NIH Postdoctoral
Fellow (1973). From Stanford he went to Pasadena to take up a faculty
appointment at the California Institute of Technology where he is now
the Bren Professor of Chemistry in the Division of Chemistry and
Chemical Engineering.
Peter Dervan has created a new field of bioorganic chemistry with
studies directed toward understanding the chemical principles for the
sequence specific recognition of the genetic material, DNA. Dervan
has combined the art of synthesis, physical chemistry, and biology to
create novel synthetic molecules with affinities and sequence
specificities comparable to Nature's proteins for any predetermined
DNA sequence. This non- biological approach to DNA recognition
underpins the design of cell-permeable molecules for the regulation
of gene expression in vivo. The approach could have profound
implications for human medicine.
Dervan is a member of the National Academy of Sciences, the Institute
of Medicine, the American Academy of Arts & Sciences, and a
Foreign Member of the French Academy of Sciences. His awards include
the Harrison Howe Award (1988), Arthur C. Cope Award (1993), Willard
Gibbs Medal (1993), Nichols Medal (1994), Maison de la Chimie
Foundation Prize (1996), the Remsen Award (1998), Kirkwood Medal
(1998), the Alfred Bader Award (1999), the Max Tishler Prize (1999),
the Linus Pauling Award (1999), and the Richard C. Tolman Medal
(1999).
Professor Dervan's curriculum
vitae