Andrew Joseph Ransick
Education
B.A. New College of the University of South Florida 1982 (Natural Sciences)
M.S. California Stazte University, Northridge 1984 (Cell and Developmental Biology)
Ph.D. University of Texas, Austin 1988 (Zoology)
Current Research Interests
Areas of Interest: Cell and Developmental Biology-Experimental Embryology
Specific Focus: Investigate mechanisms by which cell fate is specified in early embryogenesis.
Research Plan: Use a combination of microsurgical,cytological and molecular approaches to investigate the mechanisms of determinative events.
Professional Societies
Society for Developmental Biology
American Society for Cell Biology
American Society of Zoologists (1982-85)
PUBLICATIONS
Ransick,A (1991) Reproductive Cell Specification During Volvox obversus Development. Dev.Biol. 143: 185-198.
Ransick, A and Davidson, E.H. (1993) A complete Second Gut Induced by Transplanted Micromeres in the Sea Urchin Embryo, Science 259: 1134-1138.
Ransick, A., Ernst, S., Britten, R.J. and Davidson, E.H. (1993) Whole Mount In Situ Hybridization Shows Endo 16 to be a Marker for the Vegetal Plate Territory in Sea Urchin Embryos. Mech. of Develop. 42: 117-124.
Ransick, A.(1993) Specification of Reproductive Cells in Volvox. In Evolutionary Conservation of Development Mechanisms, pg. 55-70, (A Spradling ed.), Wiley-Liss, N.Y.
Kirk, M.M., Ransick, A., MacRae, S.E.,and Kirk, D.L. (1993) The Relationship between Cell Size and Cell Fate in Volvox carteri. J.Cell Biology, 123: 191-208.
Yuh, C.H., Ransick, A., Martinez, P., Britten, R.J. and Davidson, E.H. (1994) Complexity and organization of DNA-Protein Interactions in the 5'-Regulatory Region of an Endoderm-Specific Marker Gene in the Sea Urchin Embryo. Mech.of Dev. 47: 165-186.
Ransick, A. and Davidson, E.H. (1995) Micromeres are required for Normal Vegetal Plate Specification in Sea urchin Embryos. Development 121: 3215-3222.
Ransick, A., Cameron, R.A. and Davidson, E.H. (1996) Post-embryonic segregation of the germ line in sea urchins, in relation to indirect development. Proceedings of the National Academy of Science 93: 6759-6763.
Ransick, A. and Davidson E.H. (1998) Late specification of veg1 lineages to endodermal fate in sea urchin embryos. Dev Biol. 195: 38-48.
Davidson EH, Cameron RA, Ransick A. (1998) Specification of cell fate
in the sea urchin embryo: summary and some proposed
mechanisms. Development 125: 3269-90. Review
Rast JP, Amore G, Calestani C, Livi CB, Ransick A, Davidson EH. (2000)
Recovery of developmentally defined gene sets from high-density cDNA macroarrays.
Dev Biol. 228: 270-86.
Ransick A, Rast JP, Minokawa T, Calestani C, Davidson EH. (2002) New early
zygotic regulators expressed in endomesoderm of sea urchin embryos discovered
by differential array hybridization.
Dev Biol. 246:132-47.
Davidson, E.H., Rast, J.P., Oliveri, P., Ransick, A., Calestani, C., Yuh,
C.H., Minokawa, T., Amore, G., Hinman, V., Arenas-Mena, C., Otim, O., Brown,
C.T., Livi, C.B., Lee, P.Y., Revilla, R.,
Rust, A.G., Pan, Z., Schilstra, M.J., Clarke, P.J., Arnone, M.I., Rowen,
L., Cameron, R.A., McClay, D.R., Hood, L., Bolouri, H. A genomic regulatory
network for development.(2002)
Science 295:1669-78. Review.
Amore G, Yavrouian RG, Peterson KJ, Ransick A, McClay DR, Davidson EH.
(2003) Spdeadringer, a sea urchin embryo gene required separately in skeletogenic
and oral ectoderm gene regulatory networks. Dev Biol. 261: 55-81.